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General
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A
protease is any enzyme that conducts
proteolysis, that is, begins protein catabolism
by hydrolysis of the peptide bonds that link
amino acids together in the polypeptide chain.
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Proteases occur naturally in all organisms and
constitute 1-5% of the gene content.
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Proteases are also a type of exotoxin, which is
a virulence factor in bacteria pathogenesis.
Bacteria exotoxic proteases destroy
extracellular structures.
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Protease is the digestive
enzyme needed to digest protein.
Process
- Production
of protease is done by a local wild-type strain, Aspergillus
terreus IMI 282743 using pre-filtered palm oil mill effluent.
- Protease
is produced by submerged cultivation and Solid state
cultivation.
Market
- Microbial
proteases, which play a specific catalytic role in the
hydrolysis of protein, are indeed one of the most important
groups of industrial enzymes and account for about 60% of the
total worldwide enzyme sales.
Applications
- Alkaline
proteases are extensively used in detergents, leather
processing, silver recovery, medical purposes, food processing,
feeds and chemical industries as well as waste treatment.
- Proteases
regulate many biological pathways in humans and are components
of several bacterial toxins.
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