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General
- Paracetamol (INN) or
acetaminophen (USAN) is a widely-used analgesic and antipyretic.
- Paracetamol has been
in use as an analgesic for home medication for over 30 years.
- The effectiveness of
paracetamol was discovered without knowing how it works.
Mechanism
- The proposed
mechanism for an interaction between paracetamol use and asthma,
depletion of glutathione in lung tissue, was criticised as 'biologically
implausible'
- Paracetamol is
primarily metabolised by the liver.
- Paracetamol and its
two primary metabolites are remarkably safe compounds, and the
hepatotoxicity of paracetamol arises only through the 5% that is
oxidised.
-
Paracetamol manufacture via Nitro Benzene route is yet
to start in the country.
Uses
- Paracetamol has not
been shown to cause asthma and remains the analgesic of choice for
people with asthma.
- Paracetamol relieves
pain and fever in adults and children, and is the most widely accepted
medicine in the UK for this purpose.
- Paracetamol can be
combined with decongestant ingredients to help relieve the symptoms of
the common cold, influenza and sinusitis by relieving headache, general
aches, nasal congestion and fever.
- Paracetamol may
protect against cardiovascular disease.
Market
-
The total world market for
Paracetamol bulk drug is estimated to be about 1,10,000 tonnes per
annum, with Europe and North America accounting for nearly 40% of the
total market.
-
USA, Germany, Turkey, China and
India are the leading producers of Paracetamol bulk drug.
-
The domestic market for
paracetamol has grown substantially in the last decade.
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Exports of paracetamol is likely
to grow at an average annual growth rate of 15% considering the
tremendous scope that exists for export of paracetamol.
Entrepreneur who want the
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Technology, Uses, Safety, Guides, Management, Consultants, Company Profiles, Reports,
Market" can E-Mail us to
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Mechanism,
Technology, Uses, Safety, Guides, Consultants, Company Profiles, Reports,
Market
