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                                         Information @ a Glance
  • Octanol is a straight chain fatty alcohol with eight carbon atoms and the molecular formula CH3(CH2)7OH.

  • Octanol (2-ethyl-hexanol) is a colorless liquid with a specific odor. The product is little soluble in water. It is combustible and flammable.

  • By heating to decomposition, 2-ethylhexanol gives carbon monoxide and dioxide. It can also give irritant and corrosive gases.

  • Octanol is a toxic and flammable product.

  • At heating over 75 ºC, octanol vapors give explosive mixtures with air.

  • Octanol vapors produce eyes and skin irritation, dizziness and headaches.
  • Although the term octanol usually refers exclusively to the primary alcohol 1-octanol, there are other less common isomers of octanol such as the secondary alcohols 2-octanol, 3-octanol and 4-octanol.
  • Octanol occurs naturally in the form of esters in some essential oils. The primary use of octanol is in the manufacture of various esters (both synthetic and naturally occurring), such as octyl acetate, which are used in perfumery and flavors.
  •  Other uses include experimental medical applications utilizing octanol to control Essential Tremor and other types of involuntary neurological tremors.
  • Octanol is produced industrially by the oligomerization of ethylene using triethylaluminium followed by oxidation of the alkylaluminium products.
  • Octanol and water are immiscible. The distribution of a compound between water and octanol is used to calculate the partition coefficient 'P' of that molecule .
  • Water/ octanol partitioning is a good approximation of the partitioning between the cytosol and lipid membranes of living systems.
  • Many dermal absorption models consider the stratum corneum/ water partition coefficient to be well approximated by a function of the water/ octanol partition coefficient of the form
     

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