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General
- The active
ingredient, mancozeb, is a fungicide in a subclass of carbamate
pesticides called dithiocarbamates.
- Mancozeb is a
grayish-yellow powder with a musty odor which is practically insoluble
in water as well as most organic solvents.
- It is a polymer of
maneb combined with zinc.
- Mancozeb is marketed
by the trade names Dithane, Manzeb, Nemispot, and Manzane.
- The primary concern
with mancozeb is its spontaneous degradation to ethylenethiourea (ETU)
in the presence of water and oxygen.
- Mancozeb has a very
low acute toxicity to mammals.
Process
- The physical modes of
action of azoxystrobin, mancozeb, and metalaxyl were evaluated on
grapevine seedlings using Plasmopara viticola as a model pathogen.
- Two cohort mortality
studies have mentioned the possibility of exposure to mancozeb, however,
these cohorts had a very small number of cases and data on potential for
exposure to mancozeb were lacking, making these studies less useful for
an evaluation of mancozeb’s carcinogenic potential.
- Seeds of both the
species (common and Tartary buckwheat) were treated with three different
fungicides, namely bavistin (carbendazim 50 WP) 0.1%, raxil (tebuconazole
2%) 0.1% and ridomil MZ 72 WP (metalaxyl 8%+mancozeb 64% WP) 0.25%.
Application
- Mancozeb is an
ethylenebisdithiocarbamate fungicide used against a wide range of fungal
diseases of field crops and fruits.
- Mancozeb is used as a
protective fungicide (to prevent fungal growth) and in foliar and seed
treatments to control a wide range of pathogens in field crops, fruits,
ornamentals and vegetables.
- Synthetic pyrethroids
such as azodrin, cypermethrin, deltamethrin, fenvalerate and mancozeb
are used for seed treatment of cereal grains, cotton, tomatoes etc., and
for the control of undesirable insects in order to increase agricultural
production.
- The seed treated with
high concentrations of mancozeb was effective in reducing common scab
disease caused by infected seed.
Report
- It has been reported
that the uses with a combi-formulation (grapevines, tomatoes, potatoes)
containing besides benthiavalicarb-isopropyl also mancozeb, the consumer
risk assessment could not be completed, since no assessment with regard
to mancozeb residues was carried out.
- Mancozeb, maneb and
propineb were reviewed in the periodic review programme and MRLs for
dithiocarbamates were recommended.
- Five eye irritation
studies were conducted with mancozeb technical material where all five
eye irritation studies clearly shows that the ocular irritation
potential of mancozeb is low and that R36 labelling is not warranted.
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