Lipoic acid                                                                     General, Production, Technology, Applications, Patent, Consultants, Company Profiles, Reports, Market                                                           Primary Information Services                                                    Home. Ordering Information. Contact

                                         Information @ a Glance
General
  • Lipoic acid is an antioxidant found in certain foods, including red meat, spinach, broccoli, potatoes, yams, carrots, beets, and yeast. It is also made in small amounts in the human body.
  • Lipoic acid plays an important role in metabolism. Recent research has shown that it is beneficial in treating nerve damage in diabetics. It is an antioxidant that is promoted to protect the body against cancer and other diseases.

Production

  • Fatty acid and lipoic acid biosynthesis were investigated in plant mitochondria. Although the mitochondria lack acetyl-CoA carboxylase,  experiments reveal that they contain the enzymatic equipment necessary to transform malonate into the two main building units for fatty acid synthesis: malonyl- and acetyl-acyl carrier protein (ACP).

  • Alpha-lipoic acid protects mitochondria by removing free radicals and improves the recycling of other antioxidants. Carnitine is more potent in restoring mitochondrial energy production. Thus the combination is complementary.

Application

  • Alpha-lipoic acid may prove useful in the treatment of chronic hepatitis because it relieves stress on the liver and helps rid the body of toxins.It has also been used in conjunction with silymarin to treat Amanita poisoning.

  •  Alpha Lipoic Acid Plus combines ALA with other antioxidants (vitamins C, E and Pine bark extract) to potentiate its effectiveness.

  •  Pine bark extract is an antioxidant that helps prevent nitric oxide deficiencies.

  •  Alpha Lipoic Acid Plus is easily absorbed and readily bioavailable

Market

  • Japan has also recently approved alpha-lipoic acid as a food, a development that is likely to further boost the current double-digit growth in the antioxidant.
  • Degussa produces alpha-lipoic acid, marketed as Alipure, under a patented chemical synthesis process. The new formula will be produced, without solvents, in Wacker's cyclodextrins plant in Eddyville in the US.
  • Degussa is also planning to offer its Alipure product in a liquid formulation for beverages and soft gels, probably by the end of the first quarter. Early trials on this version suggest that it offers improved bioavailability over standard alpha-lipoic acid.

Report

  • Alpha-lipoic acid has been described in scientific publications as the “ideal,” “universal,” and “metabolic” antioxidant. At high doses, alpha-lipoic acid helps maintain normal blood sugar balance in certain populations, and it also helps protect the liver and other tissues.
  • Degussa's new alpha-lipoic acid has been microencapsulated on a molecular level with alpha-cyclodextrin produced by chemicals group Wacker, giving it a much-improved shelf life and taste.

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