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General
- Glycine
(abbreviated as Gly or G) is the organic compound with the formula
NH2CH2COOH.
- Glycine is
the smallest of the 20 amino acids commonly found in proteins,
coded by codons GGU, GGC, GGA and GGG.
- Glycine has
specialized structural properties in protein architecture, and
hence this compact amino acid is often evolutionarily conserved.
- Glycine is
unique among the proteinogenic amino acids in that is not chiral.
Most proteins contain only small quantities of glycine.
Process
- Glycine is
manufactured industrially, either by treating chloroacetic acid
with ammonia or via the Strecker amino acid synthesis.
- Glycine is
a building block to numerous natural products. In higher
eukaryotes, D-Aminolevulinic acid, the key precursor to
porphyrins, is biosynthesized from glycine and succinyl-CoA.
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Glycine is an inhibitory neurotransmitter in the central nervous
system, especially in the spinal cord, brainstem, and retina.
Application
- Glycine
is used as a sweetener or taste enhancer, buffering agent,
reabsorbable amino acid.
- Glycine
is used as chemical intermediate, metal complexing agent.
- Glycine
is a dietary supplement in certain pharmaceuticals.
Report
- United
States manufacturer of Glycine, GEO Specialty Chemicals,
Inc. filed petitions requesting that antidumping duties also
be imposed on Glycine imported from Japan, the Republic of
Korea, and India.
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Glycine imported from China to the United States has been
subject to antidumping duties.
- The
Commission found that changes in glycine prices are unlikely
to affect the quantity demanded because glycine is an
intermediate product with no substitutes .
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