Eugenol - General, Production Process, Properties, Company Profiles, Patent, Technology, Applications, Report

General

Eugenol (C10H12O2), is an allyl chain-substituted guaiacol.
Eugenol is a member of the phenylpropanoids class of chemical compounds.
It is a clear to pale yellow oily liquid extracted from certain essential oils especially from clove oil, nutmeg, cinnamon, and bay leaf.
It is slightly soluble in water and soluble in organic solvents. It has a pleasant, spicy, clove-like aroma.
Eugenol is sometimes called clove oil because it is the active element in cloves.
Besides cloves, it can also be extracted from cinnamon and other aromatic spices.

Process

Essential oils are volatile, ethereal liquids of oily consistency. They are extracted from plants, usually by steam distillation or extraction.
Eugenol is the main ingredient of the essential oil that can be isolated from the spice clove.
Eugenol contains a carbon-carbon double bond and an aromatic hydroxyl group called a phenol. These functional groups provide the basis for simple chemical tests used to characterize the clove oil.

Applications

Eugenol is used in perfumeries, flavorings, essential oils and in medicine as a local antiseptic and anesthetic.
It is a key ingredient in Indonesian kretek (clove) cigarettes.
Eugenol derivatives or methoxyphenol derivatives in wider classification are used in perfumery and flavoring.
They are used in formulating insect attractants and UV absorbers, analgesics, biocides and antiseptics. They are also used in manufacturing stabilizers and antioxidants for plastics and rubbers.
Eugenol is a phenol derivative that is used in combination with zinc oxide as a surgical dressing, pulp capping agent, cavity liner, temporary cement, and in mouthwashes and endodontic therapy.
Eugenol is found as a major ingredient in a variety of dental materials such as impression materials, filling materials, dental cements, endodontic sealers, periodontal dressing materials and dry socket dressings.

Report

Eugenol was the compound responsible for antifungal activity of the essential oil of O. gratissimum.
The capacity of a zinc oxide-and eugenol-based root canal sealer in penetrating into lateral canals depends on two factors: the physical properties of the material and the correct manipulation of the sealer, respecting the powder-liquid ratio and observing the ideal clinical consistency for obturation, which is more important and, also, more controllable by the dentist.
Eugenol is widely used in dentistry. It is generally used without incident however in a sensitised individual it can cause a range of tissue effects, from low-grade local reactions to the rare, but serious, anaphylactic reaction.
Eugenol is not a bio-friendly material and patients should be discouraged from using it in its pure form, either to alleviate toothache or dentine hypersensitivity.
Eugenol containing materials need to be used in the appropriate amounts and manufacturer's instructions should be followed. For patients who are allergic to eugenol, eugenol-free alternatives are available.

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