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General
Information
- The term
“diagnostic enzymes” refers to enzymes used directly or as a
component of an assay system for the determination of many
different substances.
- Common
enzymes used for clinical diagnosis include: acid phosphatase,
alanine aminotransferase , alkaline phosphatase , amylase ,
angiotensin converting enzyme, aspartate aminotransferase,
cholinesterase , creatinine kinase , gamma glutamyltransferase ,
lactate dehydrogenase , renin.
Technology
- Recent
advances in recombinant DNA technology have made it possible to
clone numerous genes of interest and to manipulate bacterial,
yeast, insect, and mammalian cells to overproduce the desired
enzyme.
- The
in-vitro diagnostic (IVD) industry is experiencing rapid
technological developments. The IVD market is estimated to grow
25 percent annually.
Application
-
The Diagnostics
Products group provides products for use in clinical
laboratories and at the point of care in a variety of formats
from clinical chemistry products to rapid tests.
- Diagnostic
enzymes are important for analysis of samples of blood, serum,
and urine for monitoring and diagnosing diseases.
- Enzymes
are used for signal and target amplification to improve the
sensitivityand speed of immunoassays or to enable the
multiplication of nucleic acid fragments.
Market
- The
diagnostic and research and biotech markets will post
near-average growth, benefiting from investment in
biotechnology and genetics and the continued development of
self-diagnostic kits.
- The
various global target markets for diagnostic products are very
broad and include individual end users, medical practitioners,
small, medium, and large clinics and hospitals, and government
agencies.
-
Pharmaceuticals will remain the largest enzyme market, due
principally to the rapid expansion of the orphan drug market for
treating lysosomal storage disorders.
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Products,
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Future and Company Profiles
