General
- Calcium
gluconate is a mineral supplement. It is the form of calcium
most widely used in the treatment of hypocalcemia.
- Calcium
Gluconate, is white in colour and is available in the form of a
crystalline powder or granules. Calcium Gluconate is found to be
highly effective in the treatment of calcium deficiencies
Process
- The waste
mycelium of Penicillium
chrysogenum HA-10 (obtained at the end of penicillin
fermentation), or a 24-hr-old freshly grown vegetative inoculum
of this organism, was found to utilize glucose for the
production of calcium gluconate by submerged fermentation in
shake flasks.
- Calcium
Gluconate is produced by the electrolytic oxidation of Glucose
dissolved in sodium bromide solution used as electrolyte in a
cell having graphite electrodes. Gluconic acid formed is
neutralised by the suspended Calcium Carbonate present in the
electrolyte. Calcium Gluconate formed in the electrolyte is
recovered by cooling the the mother liquor obtained after
recovery of the product is continuously reused in further
batches
Uses
- Calcium
Gluconate - product of the process of electrolytic oxidation of
glucose , is used as a dietary supplement for the treatment of
patients with a calcium deficiency .Other than its use as a
medicine, Calcium Gluconate has also found its rightful place in
several other industries. It is used instead of fruit acids in
making fruit jellies and baking powders. Calcium Gluconate also
provides the base for producing ferrous gluconate which is used
in the treatment of patients having an iron deficiency .
- Calcium
Gluconate is extensively used in the treatment of Calcium
deficiency, both for oral and parenteral administration. It is
also used as an oral antidote for fluorine and onalic acid
poisoning and as a substitute for fruit acids in the manufacture
of fruit jellies and baking powders and in the preparation of
homogeneous pastes like dentifrices and metal polishes; ferrous
gluconate which can be readily made from Calcium Gluconate is
used in the treatment iron deficiency and in tonic compositions.
Aluminium Gluconate has potential use as a tanning agent
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