General
-
Bioperine® is a
standardized extract from the fruit of
Piper nigrum L (black pepper) or
Piper longum L (long pepper). It contains 95 percent of piperine.
Bioperine® may be co-administered with various
nutrients for both human and animal health. Bioperine®
extract obtained from the black pepper fruit that is cultivated in the
damp, nutrient-rich soil regions of southern India .
- The delicate
pepper berries are harvested just prior to ripening and then sun dried
to assure optimum maturity and quality. The extract of piperine, called
Bioperine® in the patented form, has been
clinically tested in the United States . Bioperine®
significantly enhances the bioavailability of various supplement
nutrients through increased absorption.
Extraction
Process
- A bioassay-guided
isolation of the ethanol extract from the fruits of Piper longum
yielded a known piperidine alkaloid, piperine, as a monoamine
oxidase (MAO) inhibitor. Piperine showed an inhibitory effect. Some
results suggest that piperine possesses potent antidepressant-like
properties that are mediated in part through the inhibition of MAO
activity, and therefore represent a promising pharmacotherapeutic
candidate as an antidepressant agent.
- It is interesting
to note that the proportions of piperin can vary the simple one with
the double according to pepper and that while following the same
protocol of extraction. Piperin is presented in the form of pale
crystals yellow, with iridescent reflections, melting between 127
and 130°C. The crystals are prismatic, to four sides, and belong to
the monoclinical system.
Applications
- The advantage of
utilizing black pepper (as opposed to the standard quinine) in the
treatment of refractory intermittent fevers, which are symptomatic
of malarial infections. It was reported that long pepper was used
for patients with chronic malaria with splenomegaly (enlarged
spleen). The use of black pepper, long pepper, or trikatu is
traditionally well-known in the treatment of a variety of
gastrointestinal disorders, and all three act to improve digestion.
- Best Curcumin
w/Bioperine contains a standardized extract of Curcuma longa root,
commonly known as “Turmeric.” Turmeric is a yellow spice used in
curried dishes. In the Far East, turmeric is valued for more than
just its culinary applications. Bioperine is added as a natural
bioenhancer to promote absorption of the product.
Market &
Report
- World Pepper
production, as per International Pepper Community (IPC) projection,
of around 300,000 metric tons during 2003 is dominated by Asia
region accounting for 65-70% of total production. The region caters
for three-quarters of the total export market. This facts clearly
portray the importance that the Asian region has in the world pepper
trade.
- In India, pepper
vines usually flower during May to June with the commencement of the
monsoon. It takes about six to eight months from flowering to
harvest. The main harvesting season is from November- December in
the plains and January to March in the hills. India dominates world
pepper market given its consumption and production pattern.
- When volunteers
took Bioperine® (a proprieary black pepper extract) along with
certain nutrients, blood levels of the nutrients were significantly
higher in the extract group than in the blood levels of the placebo
group. Piperine, is a patent-pending form of "Bioperine" which has
been proved in medical trials and research to enhance the body’s
natural thermogenic activities.
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