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General
- Aspirin,
or acetylsalicylic acid , is a salicylate drug, often used as an
analgesic to relieve minor aches and pains, as an antipyretic to reduce
fever, and as an anti-inflammatory medication.
- Aspirin
was the first-discovered member of the class of drugs known as
non-steroidal anti-inflammatory drugs (NSAIDs).
Process
- The
synthesis of aspirin is classified as an esterification reaction, where
the alcohol group from the salicylic acid reacts with an acid derivative
(acetic anhydride), yielding aspirin and acetic acid as a byproduct.
-
Formulations containing high concentrations of aspirin often smell like
vinegar.
- This is
because aspirin can decompose in moist conditions, yielding salicylic
acid and acetic acid.
Report
- Pharmacy
and Pharmaceutical Sciences, found that up to 20 percent of patients
taking aspirin to lower the risk of suffering a second cerebro vascular
event do not have an antiplatelet response from aspirin, the effect
thought to produce the protective effect.
- That's
one of the critical pieces of information was, frequently aspirin
resistance occurred in all patients and its prevalence in patients who
suffered clinical aspirin failure.
Application
- Aspirin
is one of the most frequently used drugs in the treatment of mild to
moderate pain, including that of migraines and fever It is often
combined with other non-steroidal anti-inflammatory drugs and opioid
analgesics in the treatment of moderate to severe pain.
- Aspirin
has been used to treat pain and arthritis in veterinary medicine,
primarily in cats and dogs, although it is often not recommended for
this purpose, as there are newer medications available with fewer side
effects in these animals.
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