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General
- Aleuritic Acid is
a unique acid containing three hydroxyl groups of which two are of
adjacent carbon atoms.
- Aleuritic acid
(9,10,16-trihydroxy-palmitic acid) is a major constituent acid
(~35%) of lac resin (shellac).
- Shellac is well
known as a wood finish but its principal modern-day use is as a
coating for pharmaceutical tablets.
Synthesis
- Aleuritic Acid
(9, 10, 16-trihydroxypalmitic acid), obtained from shellac by
saponification and several filtration processes.
- Aleuritic Acid is
moderately soluble in hot water and crystallises out on cooling the
solution.
Application
- Aleuritic Acid is
isolated from the resin and mainly used in the perfumery industry,
as a starting material for the preparation of "musk" aroma compounds
as well as medicinal and bioactive compounds.
- Aleuritic acid is
also an important raw material for the synthesis of the perfumery
musk compounds.
- Aleuritic Acid is
a critical component in the synthesis of macro-cyclic fragrance
chemicals such as ambrettolide, iso-ambrettolide, civetone,
dehydiocivetone, exaltone, glucose manoaleuritate and related
lactones.
- Lac and Shellac
has been used in industries such as paint, varnishes,
pharmaceuticals, and confectionaries from centuries.
Market
- The Chennai-based
ayurvedic research centre has been asked by Shellac Export Promotion
Council (SEPC) to develop ambrettolide from aleuritic acid, which is
a high value ingredient for the perfume industry.
- In the world
market, pheromone currently fetches $400 per kg and ambrettolide
fetches $200 per kg, compared to aleuritic acid, priced at $30 a kg.
- Aleuritic acid is
the highest value export from India per tonne and has shown the most
dramatic increase from 4percent by value to 7 percent.
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