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- Acetyl
chloride, also known as ethanoyl chloride, is an acid chloride
(also known as an acyl chloride) derived from acetic acid (ethanoic
acid).
- Acetyl
Chloride is a clear, corrosive and fuming liquid; melting point
of -112 C, boiling point of 51-52 C, refractive Index of 1.3890.
- Acyl
halide is one of a large group of organic substances containing
the halocarbonyl group, have the general formula RCO·X, where X
is a halogen atom (fluorine, chlorine, bromine, iodine, and
astatine) and R may be aliphatic, alicyclic, aromatic, and H
etc.
- Acetyl
chloride does not exist in nature, because contact with water
would hydrolyze it into acetic acid and hydrogen chloride.
- Acetyl
chloride is synthesized by the reaction of acetic acid
(CH3COO-H) with thionyl chloride (O=SCl2) under liberation of
sulfur dioxide (SO2).
- It is a
reagent for acetylation in the synthesis or derivatization of
chemical compounds. Examples of acetylation reactions include
acylation processes such as esterification.
- It is
widely used as an acetylating agent in the synthesis of fine
chemicals, agrochemicals and pharmaceuticals.
- It is also
used as an intermediate for dyes. It is also used to determine
water in organic liquids and in testing cholesterol.
- Acetyl
Chloride is used as an Acetylating agent ; Special chlorinated
agent for inorganic compounds , Catalyst in esterification,
halogenation of aliphatic acids and nitration of thiophenes;
Synthesis of organic intermediates , Perfume industry .
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