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General
- Gibberellic acid (also
called Gibberellin A3, GA, and (GA3) is a hormone found in
plants. Its chemical formula is C19H22O6.
When purified, it is a white-to-pale-yellow solid.
- GA was first identified
in Japan in 1935, as a metabolic byproduct of the plant pathogen
Gibberella fujikuroi (thus the name), which afflicts rice plants.
- Gibberellins have been
identified in many species (and are believed to be present in all plant
species) of plants at various amounts in all parts of plants. There are
over 125 gibberellins that vary in structure and activity; however GA3
is the most thoroughly studied.
Process
- The gibberellic
acid formed in the fermentation medium may be isolated by filtration
of the medium and extraction of the filtrate with an organic solvent
or by absorption with activated charcoal.
- GA3 has been
obtained by chemical synthesis, extraction from plants and by
microbial fermentation. Stereo specific chemical synthesis involves
multiple steps and the use of expensive reagents.
- GA3 production in
fungal culture includes liquid surface fermentation, submerged
fermentation, and solid state fermentation
Report
- It is a
high-value industrially important biochemical selling at
$27-36/g on the international market.
- Currently, GA3
is largely produced by submerged fermentation of the fungus
Gibberella fujikuroi on an industrial scale.
- The filamentous
fungus Gibberella fujikuroi is the main producer of
gibberellins. These hormones are widely used to optimise growth
in several products, particularly seedless grapes.
- Gibberellic
Acids are applied to growing crops (field crops, small fruits,
vines and tree fruits), ornamental and shade tress, and
ornamental plants, shrubs and vines.
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